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The Journal

Notes From the Road, Written by the People Who Run the Line.

Plain answers about IV therapy, GLP-1 programs and peptides — written for people in New York and New Jersey who are deciding whether any of it is worth their afternoon.

Sildenafil vs Tadalafil (Viagra vs Cialis): Which Should You Take?
Sexual Health

Sildenafil vs Tadalafil (Viagra vs Cialis): Which Should You Take?

Sildenafil works in about an hour and lasts four to six hours. Tadalafil takes a bit longer and lasts up to 36 hours, or

October 1, 2026 · 5 min read

How Long Does Sildenafil Last? Timing, Food and Dose, Explained
Sexual Health

How Long Does Sildenafil Last? Timing, Food and Dose, Explained

Sildenafil kicks in within 30 to 60 minutes and keeps working four to six hours. A big fatty meal can delay it by an hou

September 30, 2026 · 5 min read

Daily Tadalafil: Why Some Men Take a Low Dose Every Day
Sexual Health

Daily Tadalafil: Why Some Men Take a Low Dose Every Day

A 2.5 or 5 mg tadalafil every day keeps a steady level in the blood, so there is nothing to plan. It also eases urinary

September 29, 2026 · 5 min read

Premature Ejaculation: Causes and the Treatments That Actually Work
Sexual Health

Premature Ejaculation: Causes and the Treatments That Actually Work

PE is the most common male sexual complaint and one of the most treatable. A low-dose daily or on-demand medication, a n

September 28, 2026 · 5 min read

Low Libido in Men: The Real Causes and How to Get Desire Back
Sexual Health

Low Libido in Men: The Real Causes and How to Get Desire Back

Low sex drive usually traces to testosterone, sleep, stress, a medication, relationship issues or depression. Labs settl

September 27, 2026 · 5 min read

Performance Anxiety and ED: How to Break the Cycle
Sexual Health

Performance Anxiety and ED: How to Break the Cycle

One bad night becomes worry, worry becomes another bad night. The fix is usually a short course of medication to rebuild

September 26, 2026 · 5 min read

Testosterone and ED: When Low T Is the Problem and When It Is Not
Sexual Health

Testosterone and ED: When Low T Is the Problem and When It Is Not

Low testosterone lowers desire and can soften erections, but most ED is a blood-flow problem, not a hormone problem. Lab

September 25, 2026 · 5 min read

Low Testosterone in Men: The 10 Signs and How It Is Diagnosed
Hormones

Low Testosterone in Men: The 10 Signs and How It Is Diagnosed

Fatigue, low drive, softer erections, a shrinking gym, more belly, a flatter mood, poor sleep. One of these is life. Sev

September 24, 2026 · 5 min read

TRT: Benefits, Risks and What to Expect in the First Six Months
Hormones

TRT: Benefits, Risks and What to Expect in the First Six Months

Testosterone replacement brings back energy, drive and muscle in men who are truly low. It also thickens blood, can shri

September 23, 2026 · 5 min read

Enclomiphene vs TRT: Raise Your Own Testosterone or Replace It?
Hormones

Enclomiphene vs TRT: Raise Your Own Testosterone or Replace It?

Enclomiphene tells your body to make more testosterone. TRT replaces it from outside. Enclomiphene keeps fertility and i

September 22, 2026 · 5 min read

How to Raise Testosterone Naturally: What Works and What Is Hype
Hormones

How to Raise Testosterone Naturally: What Works and What Is Hype

Sleep, losing belly fat, lifting weights, limiting alcohol and fixing vitamin D move testosterone meaningfully. Most sup

September 21, 2026 · 5 min read

Does TRT Cause Hair Loss? What to Know Before You Start
Hormones

Does TRT Cause Hair Loss? What to Know Before You Start

TRT does not cause hair loss by itself, but more testosterone means more DHT, and if your follicles are DHT-sensitive it

September 20, 2026 · 5 min read

How Semaglutide Works for Weight Loss, in Plain English
Weight Loss

How Semaglutide Works for Weight Loss, in Plain English

Semaglutide copies a gut hormone that tells your brain you are full, slows your stomach, and quiets the constant thought

September 19, 2026 · 5 min read

Semaglutide Side Effects: What Is Normal, What Is Not, and How to Manage Each One
Weight Loss

Semaglutide Side Effects: What Is Normal, What Is Not, and How to Manage Each One

Nausea, constipation, fatigue and burping are the common ones, mostly in the first weeks after each dose increase. Serio

September 18, 2026 · 5 min read

Ozempic Face: What It Is, Why It Happens and How to Prevent It
Weight Loss

Ozempic Face: What It Is, Why It Happens and How to Prevent It

Ozempic face is the hollow, saggy look some people get from losing fat quickly, including the fat that makes a face look

October 17, 2026 · 5 min read

Compounded Semaglutide vs Ozempic and Wegovy: What Is Actually Different
Weight Loss

Compounded Semaglutide vs Ozempic and Wegovy: What Is Actually Different

The active ingredient is the same molecule. Brand is an FDA-approved pen; compounded is made by a licensed pharmacy for

October 16, 2026 · 5 min read

Hit a Plateau on Semaglutide or Tirzepatide? Here Is Why and What to Do
Weight Loss

Hit a Plateau on Semaglutide or Tirzepatide? Here Is Why and What to Do

Plateaus are normal: the body adapts, the dose stops being enough, or small habits creep back. A dose step, a protein ch

October 15, 2026 · 5 min read

What Happens When You Stop Semaglutide? Regain, Tapering and Maintenance
Weight Loss

What Happens When You Stop Semaglutide? Regain, Tapering and Maintenance

Appetite comes back within weeks, and without a plan most people regain much of the weight within a year. A taper, a low

October 14, 2026 · 5 min read

What Is Food Noise, and Why GLP-1s Turn It Off
Weight Loss

What Is Food Noise, and Why GLP-1s Turn It Off

Food noise is the constant background thinking about what to eat next. For many people it is the real reason diets fail.

October 13, 2026 · 5 min read

Can You Drink Alcohol on Semaglutide or Tirzepatide?
Weight Loss

Can You Drink Alcohol on Semaglutide or Tirzepatide?

A drink or two is fine for most people. Many find they want less. Alcohol plus a slowed stomach can worsen nausea and lo

October 12, 2026 · 5 min read

Wegovy vs Zepbound: Semaglutide vs Tirzepatide, Compared Honestly
Weight Loss

Wegovy vs Zepbound: Semaglutide vs Tirzepatide, Compared Honestly

Zepbound (tirzepatide) produced more weight loss in head-to-head trials, about 20 percent versus 15. Wegovy (semaglutide

October 11, 2026 · 5 min read

GLP-1 Pills: Oral Semaglutide, Sublingual Options and What Is Coming
Weight Loss

GLP-1 Pills: Oral Semaglutide, Sublingual Options and What Is Coming

Pills exist and more are coming, but the weekly injection is still the most reliable way to get the full effect. Here is

October 10, 2026 · 5 min read

Microdosing GLP-1s: Who It Is For and What It Can Do
Weight Loss

Microdosing GLP-1s: Who It Is For and What It Can Do

Tiny doses of semaglutide or tirzepatide, below the usual starting dose, for appetite control without the side effects.

October 9, 2026 · 5 min read

Metformin for Weight Loss: What It Can and Cannot Do
Weight Loss

Metformin for Weight Loss: What It Can and Cannot Do

Metformin is cheap, well understood and helps blood sugar and insulin resistance. For weight it produces a modest five t

October 8, 2026 · 5 min read

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