Retatrutide acts on GIP, GLP-1 and glucagon receptors together. Early trial data shows the largest average weight loss of any agent in its class so far, though it remains investigational and is not yet FDA-approved for weight management.
✓Largest average weight loss reported in early trials
✓Once-weekly dosing
✓Close provider monitoring given its investigational status
✓Unlimited messaging with your provider
How It Works
From Booking to Your Sofa
01
Labs and History
A full metabolic panel, thyroid, A1c and lipids, plus a real conversation about what you have already tried and what went wrong.
02
A Provider Prescribes
If the therapy suits you, your provider writes the starting dose and a titration schedule. If it does not, we say so and refund the consult.
03
Titrate and Check In
Monthly check-ins, unlimited messaging and dose adjustments as your body responds. Refills ship straight to you on your schedule.
What to Expect
Before, During and After
Before
Labs are drawn first and reviewed by your provider before anything is prescribed. Bring current medications, supplements and any prior weight or treatment history.
During
Your first injection is taught in person. The dose itself takes seconds; the teaching visit takes about twenty minutes, including what to do about side effects.
After
Message your provider at any point. Check-ins are monthly, doses escalate no faster than every four weeks, and labs repeat at week twelve.
Evidence & safety
What the Science Actually Supports
Retatrutide is investigational and not yet FDA-approved — we say so plainly and only offer it after a full discussion of what is and is not yet known. The contraindication profile is assumed to mirror other incretin therapies until longer-term data confirms otherwise. If you want a fully established therapy, ask your provider whether semaglutide or tirzepatide is the better-proven fit.
Screened for contraindications at every visit. Not intended to diagnose, treat, cure or prevent any disease. Speak with your provider if you are pregnant, nursing, or managing kidney, liver or cardiac conditions.
Farima was both extremely professional as well as competent and caring. They spent a lot of time with us, catering exactly what we needed medically and whole body wellness wise as well. They got here on time and on a weekend - it really made us feel cared for in a way we wouldn't at an urgent care or after hours at the ER. Totally worth the money - which was extremely affordable compared to clinics, etc and we had the added benefit of not having to leave the house! We definitely recommend!!!
Samantha Hubbard
Local Guide · 21 reviews · 11 photos
★★★★★1 month ago
Truly a wonderful experience! They were professional, friendly and knowledgeable. I learned a lot and feel so much better. Will definitely use them again!
Kristyn Cardali
3 reviews
★★★★★2 months ago
Farima is truly the best. As someone with a chronic illness who needs IVs regularly, it can be really difficult to find nurses who are both skilled and genuinely caring. They always make me feel comfortable, listened to, and cared for the entire time. They are incredibly gentle, always get my veins easily, and make sure everything is done perfectly and professionally. You can tell they truly care about their patients and want the experience to be as stress-free as possible. I'm so grateful for their kindness, patience, and expertise!! I would recommend them to anybody who Is looking for a great IV experience 😊
Questions We Get
Do I need labs first?+
Yes — always, for any prescription therapy. We arrange a draw at your home or a lab near you, and results are usually back within three business days.
What are the side effects?+
Nausea, early fullness and constipation are the common ones with GLP-1s, and they are usually dose-related. Slow titration is the main defence, which is why we do not rush it.
What does the price include?+
The monthly program fee covers your provider, labs review, titration, unlimited messaging and check-ins. Medication is billed separately and varies by dose.
What happens if I stop?+
Weight regain is common after stopping GLP-1s without a maintenance plan. Your provider will build one with you before you taper — that conversation is part of the program.
Why would I pick this over tirzepatide?+
Usually because you plateaued on tirzepatide. If you have not tried the others, the provider will often start there.
Is it safe?+
The trial safety profile looks like the other GLP-1s plus a higher heart rate. It is investigational; we monitor closely.
How long does a course run?+
Most people run 6–12 months then taper, like the other agents.
One monthly credit toward any drip, member pricing on every add-on and program, and priority same-day booking anywhere we serve. Pause any month; cancel any time.
Retatrutide works on three receptors: GLP-1 and GIP like tirzepatide, plus glucagon, which raises energy burn. It is the newest agent in the class and is still in late-stage trials.
Early. Phase 2 showed about 24% loss at 48 weeks; phase 3 is ongoing and it is not FDA-approved for anything yet. We prescribe it only after a conversation about that.
Here is how the visit usually feels, from the chair to the next morning.
Week 1–4Low dose, appetite drop, possible nausea or faster heart rate.
Month 2–3Careful step-ups; provider watches heart rate and blood pressure.
Month 4+Trial data suggest the largest average loss in the class, but we go slower than the trials did.
Safety, in plain words
Do not use with a personal or family history of medullary thyroid cancer or MEN2, a history of pancreatitis, during pregnancy or breastfeeding, or with type 1 diabetes unless your endocrinologist agrees. Common: nausea, constipation, fatigue and reflux in the first weeks, usually easing as the dose settles. Rare but serious: pancreatitis, gallbladder problems, severe dehydration. Stop and call us for severe stomach pain. Because glucagon raises heart rate, we also screen for arrhythmia and uncontrolled blood pressure.
How we keep an eye on you
A nurse draws a metabolic panel, A1c, lipids and thyroid at your home before the first prescription and every twelve weeks. Your provider reviews weight, appetite and side effects by message every month and adjusts the dose; you are only charged for a refill after they approve it. We add a resting heart-rate and blood-pressure check at each review.
The Zen IV Difference
✓
Licensed US pharmaciesCompounded in state-licensed 503A pharmacies in the United States, to a prescription written for you.
✓
Every batch testedPurity and potency tested by a third-party lab. Ask for the certificate on any vial and we send it.
✓
Overnight, cold, to your doorRefrigerated shipping anywhere in New York or New Jersey, with needles, swabs and a sharps container in the box.
✓
A nurse if you want oneFor injectables, a licensed RN can come for your first dose and show you how. The app-based clinics cannot do that.
Get the free guide: The complete guide to IV Therapy
What is in the bag, what a drip actually does, when you do not need one, and what to ask any mobile IV company. 6 pages, plain English, from the Zen IV Spa Medical Team.
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