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MOTS-C
Metabolic · Exercise mimetic

MOTS-C

MOTS-C is produced inside the mitochondria and appears to activate some of the same pathways as exercise itself. Early research focuses on metabolic health and insulin sensitivity rather than weight loss directly.

$229 per month, all-inclusive

Time

2–3× weekly

Cadence

Quarterly review

Where

Shipped to you

What's Inside

MOTS-C — 2–3× weekly subcutaneous, dosed at consult Baseline labs — A1c, CMP, lipids Quarterly review — Tracks metabolic markers

What It's Good For

✓Studied for insulin sensitivity and metabolic health
✓Pairs with a training block rather than replacing one
✓Quarterly labs track real markers, not just the scale
✓Provider-managed dosing
How It Works

From Booking to Your Sofa

01

Labs and History

A full metabolic panel, thyroid, A1c and lipids, plus a real conversation about what you have already tried and what went wrong.

02

A Provider Prescribes

If the therapy suits you, your provider writes the starting dose and a titration schedule. If it does not, we say so and refund the consult.

03

Titrate and Check In

Monthly check-ins, unlimited messaging and dose adjustments as your body responds. Refills ship straight to you on your schedule.

What to Expect

Before, During and After

Before

Labs are drawn first and reviewed by your provider before anything is prescribed. Bring current medications, supplements and any prior weight or treatment history.

During

Your first injection is taught in person. The dose itself takes seconds; the teaching visit takes about twenty minutes, including what to do about side effects.

After

Message your provider at any point. Check-ins are monthly, doses escalate no faster than every four weeks, and labs repeat at week twelve.

Evidence & safety

What the Science Actually Supports

MOTS-C research is early-stage and mostly preclinical or small human studies — we treat it as a metabolic adjunct, not a proven weight-loss therapy, and say so directly. Not appropriate during pregnancy or active malignancy.

Screened for contraindications at every visit. Not intended to diagnose, treat, cure or prevent any disease. Speak with your provider if you are pregnant, nursing, or managing kidney, liver or cardiac conditions.

From Our Guests

5.0 Stars on Google

Real reviews from real visits. Read more

Christina Helferich-Polosky review photo
Christina Helferich-Polosky
7 reviews · 9 photos
★★★★★7 days ago
Farima was both extremely professional as well as competent and caring. They spent a lot of time with us, catering exactly what we needed medically and whole body wellness wise as well. They got here on time and on a weekend - it really made us feel cared for in a way we wouldn't at an urgent care or after hours at the ER. Totally worth the money - which was extremely affordable compared to clinics, etc and we had the added benefit of not having to leave the house! We definitely recommend!!!
Samantha Hubbard review photo
Samantha Hubbard
Local Guide · 21 reviews · 11 photos
★★★★★1 month ago
Truly a wonderful experience! They were professional, friendly and knowledgeable. I learned a lot and feel so much better. Will definitely use them again!
Kristyn Cardali review photo
Kristyn Cardali review photo
Kristyn Cardali
3 reviews
★★★★★2 months ago
Farima is truly the best. As someone with a chronic illness who needs IVs regularly, it can be really difficult to find nurses who are both skilled and genuinely caring. They always make me feel comfortable, listened to, and cared for the entire time. They are incredibly gentle, always get my veins easily, and make sure everything is done perfectly and professionally. You can tell they truly care about their patients and want the experience to be as stress-free as possible. I'm so grateful for their kindness, patience, and expertise!! I would recommend them to anybody who Is looking for a great IV experience 😊

Questions We Get

Do I need labs first?+

Yes — always, for any prescription therapy. We arrange a draw at your home or a lab near you, and results are usually back within three business days.

What are the side effects?+

Nausea, early fullness and constipation are the common ones with GLP-1s, and they are usually dose-related. Slow titration is the main defence, which is why we do not rush it.

What does the price include?+

The monthly program fee covers your provider, labs review, titration, unlimited messaging and check-ins. Medication is billed separately and varies by dose.

What happens if I stop?+

Weight regain is common after stopping GLP-1s without a maintenance plan. Your provider will build one with you before you taper — that conversation is part of the program.

Is it for weight loss?+

For metabolic health first; weight may follow with training.

Pairs Well With

People Also Book

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Sermorelin

A growth-hormone-releasing peptide taken nightly — for sleep quality, body composition and recovery.

Membership

Members Pay About a Third Less.

One monthly credit toward any drip, member pricing on every add-on and program, and priority same-day booking anywhere we serve. Pause any month; cancel any time.

Your MOTS-c Timeline

Step 1Week 1–2: injection routine set; early effects for sleep or energy peptides
Step 2Weeks 3–6: first clear changes (recovery, sleep, skin texture, focus)
Step 3Weeks 6–12: the main results window for most programs
Step 4Month 3: labs and a check-in; continue, adjust or cycle off

Typical course; individual results vary and the provider adjusts at each check-in.

Lab-Tested Medication

Compounded for your prescription by an state-licensed 503A pharmacy in the United States, with each batch tested by an independent lab for potency and sterility, shipped overnight in refrigerated packaging, labeled with your dose. MOTS-c is not FDA-approved; compounded by prescription; we say so plainly.

Everything You Need to Start Safely

—free video consultation with a licensed provider, one-time
—Baseline labs drawn at your home by a nurse, reviewed on video
—Medication, needles, alcohol swabs, sharps container and written dosing instructions in every shipment
—A nurse at your door for the first injection if you want one
—Provider check-ins and follow-up labs included; month to month, no contract

We accept HSA and FSA cards. We do not bill insurance; an itemized receipt (superbill) is provided for reimbursement.

MOTS-c vs. the Alternatives

AOD-9604 vs AOD-9604 / MOTS-cAOD-9604 vs MOTS-cMOTS-c vs NAD+

See every comparison →

Backed by Published Science

We cite the research we rely on and say when evidence is early. Selected studies:

Important Safety Information

MOTS-c is a prescription medication dispensed only after evaluation by a licensed provider. Common side effects: injection-site redness. Do not use if pregnant or breastfeeding, with an active cancer, or without disclosing all medications and conditions. Stop and contact your provider for any severe or unexpected reaction; for an emergency call 911. This page is general information, not medical advice, and not a promise of results.

Nurse giving an IV at home

How MOTS-C Works

MOTS-c is a peptide made by mitochondria themselves. It improves insulin sensitivity and how muscle uses fuel, and rises after exercise. Used for metabolic health and endurance.

Early. Compelling mouse data (it is sometimes called the exercise mimetic); the first human trials are small.

IV therapy at home

What to Expect

Here is how the visit usually feels, from the chair to the next morning.

Week 1–2Injections a few times a week.
Month 1–2Better workout capacity and blood-sugar stability for some.
Month 3Reassess with labs.
Safety, in plain words

Not for pregnancy or breastfeeding, or anyone with an active cancer without their oncologist's sign-off. Most common: redness or a small bump at the injection site. Compounded peptides are not FDA-approved products.

How we keep an eye on you

Monthly provider check-in by message, a mid-course review at week six, and labs at home when the peptide warrants them (growth-hormone peptides get IGF-1 and glucose). Refills are only charged after the provider approves them. Fasting glucose and A1c at week twelve.

The Zen IV Difference

✓
Licensed US pharmaciesCompounded in state-licensed 503A pharmacies in the United States, to a prescription written for you.
✓
Every batch testedPurity and potency tested by a third-party lab. Ask for the certificate on any vial and we send it.
✓
Overnight, cold, to your doorRefrigerated shipping anywhere in New York or New Jersey, with needles, swabs and a sharps container in the box.
✓
A nurse if you want oneFor injectables, a licensed RN can come for your first dose and show you how. The app-based clinics cannot do that.
Read More

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