What Sermorelin Is
Sermorelin is a growth-hormone-releasing hormone analog that prompts your own pituitary to release growth hormone. It is taken as a nightly subcutaneous injection, and most people notice it in sleep in 2 weeks; composition in 2 to 3 months.
What Semaglutide Is
Semaglutide is the GLP-1 medication in Ozempic and Wegovy, compounded; it reduces appetite and slows digestion. It is taken as a once-weekly subcutaneous injection, and most people notice it in steady loss from month two.
Side by Side
| Sermorelin | Semaglutide | |
|---|---|---|
| Best for | sleep, recovery and body composition | weight loss |
| How it is taken | nightly subcutaneous injection | once-weekly subcutaneous injection |
| Time to notice | sleep in 2 weeks; composition in 2 to 3 months | steady loss from month two |
| Price at Zen IV Spa | $229/mo | $249/mo |
| Common side effects | flushing, injection-site redness | nausea early, constipation, reduced appetite |
| FDA status | formerly FDA-approved for a pediatric use; compounded by prescription | FDA-approved medication (brand); compounded version by prescription |
Pick Sermorelin If
Your main concern is a gentle, well-studied growth-hormone starter. It is the right call when the goal is sleep, recovery and body composition and you want the simpler, more targeted option.
Pick Semaglutide If
Your main concern is meaningful weight loss where appetite is the problem. It is the right call when the goal is weight loss.
Can You Combine Them?
Yes. Semaglutide drives weight loss; sermorelin is added to protect muscle and sleep during a calorie deficit.
How to Get Either One in New York or New Jersey
Every program at Zen IV Spa is prescribed and overseen by our medical director, a licensed physician, after a video consultation and baseline labs drawn at your home. Refills ship overnight anywhere in New York or New Jersey, and a nurse can come to your door for the first dose.
Single peptides are $229 a month (glutathione $199), stacks $299, semaglutide $199, tirzepatide $299. A 2-month supply is 10% off and 3 months is 15% off. The $50 consultation is one-time.
Common Questions
Which is better, Sermorelin or Semaglutide?+
Neither is better in general. Sermorelin for sleep, recovery and body composition; Semaglutide for weight loss. The provider chooses from your labs and goals.
Which costs more?+
Sermorelin is $229/mo; Semaglutide is $199/mo at Zen IV Spa, shipping and follow-ups included.
Are they FDA-approved?+
Sermorelin: formerly FDA-approved for a pediatric use; compounded by prescription. Semaglutide: FDA-approved medication (brand); compounded version by prescription. We say so plainly on every page.
Can I switch from one to the other?+
Yes. Programs run month to month with no contract; the provider adjusts at any check-in.
How do I start?+
Book a $50 video consultation at Zen IV Spa; a nurse draws baseline labs at your home.
All treatments are medical services. Every guest is screened, and every treatment is provided only under the clearance, prescription or standing protocol of a licensed medical provider. Compounded peptides are not FDA-approved unless stated. Nothing on this page is a diagnosis or a promise of results.